Bioelectronics is an interdisciplinary field that merges biology and electronics, focusing on creating devices that can interact with biological systems or harness biological materials to develop innovative electronic components. It involves the integration of biological components, such as cells, proteins, or tissues, with electronic elements like sensors, circuits, or actuators. One primary goal is to develop bioelectronic devices that can monitor, regulate, or interface with biological processes within the body, enabling advancements in healthcare, diagnostics, and therapeutic interventions. For instance, bioelectronic implants, like pacemakers or neural stimulators, use electronic components to regulate physiological functions, providing treatments for various medical conditions.
Moreover, bioelectronics explores the potential of utilizing biological materials, such as DNA, proteins, or enzymes, in electronic applications. These bio-inspired materials can be employed in sensors, energy storage devices, or computing systems, drawing inspiration from the efficiency and complexity of biological systems to create novel electronic functionalities. The synergy between biology and electronics in bioelectronics continues to drive research and development, offering promising prospects for creating cutting-edge technologies that can revolutionize healthcare, computing, and various other fields.
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1. Crystalline Reinforced Dual-Network Hydrogel for Wearable Sensing Device — 2026 , Materials Horizons
Yannan Li, Chaolun Xu, Y Qiu, J Sun, Yifan Pan, Shogo Iwai, Shinjiro Umezu — Crystallinity-enhanced dual-network hydrogel improves mechanical and conductive performance for wearable sensing. Full details unconfirmed.
2. Gas-permeable cohesive SEBS fiber substrate enabling dense conductive network formation — 2026, Japanese Journal of Applied Physics 65(8), 080908
Shumpei Katayama, Shinjiro Umezu, Kenjiro Fukuda, Sunghoon Lee, Takao Someya — Gas-permeable, cohesive SEBS fiber substrate supports formation of dense conductive networks for skin-conformal bioelectronic devices.
3. Self-adhesive Crystal-enhanced multilayer nanofilm piezoelectric sensor for motion monitoring — 2025, Chemical Engineering Journal 508, 161150
Kewei Song, Ze Zhang, Kayo Hirose, Jianxian He, Yifan Pan, Takayuki Masuji, Ryotaro Minakawa, Shinjiro Umezu — Self-adhesive, crystallinity-enhanced multilayer piezoelectric nanofilm for wearable human motion sensing.
4. A combination of logical judging circuit and water-resistant ultrathin film PEDOT:PSS electrode for noninvasive ECG measurement — March 14, 2024, Discover Nano 19(1), 45
Kewei Song, Kayo Hirose, Kioto Niitsu, Tsubasa Sui, Hiroto Kojima, Toshinori Fujie, Shinjiro Umezu — Water-resistant PEDOT:PSS ECG electrode + auto-switching logic circuit gives stable, non-adhesive long-term ECG monitoring during daily activity.
5. An organic transistor matrix for multipoint intracellular action potential recording — September 28, 2021, PNAS 118(39), e2022300118
Yasutoshi Jimbo, Daisuke Sasaki, Takashi Ohya, Sunghoon Lee, Wonryung Lee, Faezeh Arab Hassani, Tomoyuki Yokota, Katsuhisa Matsuura, Shinjiro Umezu, Tatsuya Shimizu, Takao Someya — OECT matrix achieves true intracellular (not extracellular) multipoint action-potential recording, 93 µA max signal amplitude, 4×4 grid of 5×5 µm² transistors.
6. Simultaneous measurement of contractile force and field potential of dynamically beating human iPS cell-derived cardiac cell sheet-tissue with flexible electronics — August 12, 2021, Lab on a Chip 21(20), 3899-3909
500 nm flexible electronic sheets simultaneously capture contractile force and field potential of beating iPS-cardiac tissue, impossible on rigid substrates.